Wednesday, 29 June 2016

Tusshar Kapoor Brims With Happiness as the 39 Years Old Actor is Blessed with His Bundle of Joy Laksshya:

Bollywood has a lovely reason to celebrate. For the first time, a male actor announces the happy occasion of becoming a father to a baby as a single parent. The joy and the responsibility of becoming a single parent by a public figure like him is wonderful news. The Bollywood actor Tusshar Kapur was very happy to announce that he has been blessed with the baby boy Laksshya last week. The actor who is now 39, became the single parent of the baby boy using IVF and surrogacy, reported TOI.

In his words, the Actor said that he was thrilled to be a father. The paternal instinct in him has been overpowering his heart and mind for quite some time now. Therefore, he is thrilled beyond words to have Laksshya, now the greatest source of joy in his life. The doctor too is praising him for his sense of responsibility towards the child and his health at every stage of pregnancy.

The assisted technique of reproduction is showing the path to couples as well as the single parents like Tusshar Kapoor, who has an overpowering desire to become the parent. Nowadays, IVF is the traditional way of having a test tube baby is being welcomed by many people and surrogacy is the new way that the couples and the single parents are adopting nowadays. The new trend of becoming a parent with the help of surrogacy and IVF /In Vitro fertilization is increasing these days. Parenthood is showing new horizons, where single men or women are having the joy of becoming a parent, taking up the responsibility of the child and making new meaning of life.

Tusshar’s parents, Jitendra and Sobha are very much happy on welcoming Laksshya in their family. They said in a joint statement that they could not be more excited to be the grandparents to Laksshya and are completely supportive of their son’s decision. They said that this was certainly a tremendous blessing and an exciting time in their lives. Tusshar Kapoor is a wonderful son, and he has proven with responsibility, independence and kindness, and there is no doubt that he will be a great father to Laksshya.

The Doctor said that she was impressed with Tusshar’s determination to be a father. He maintained a keen interest in the baby’s health at every stage. He will be a sensitive and a nurturing parent.
He further added that as a public figure, Tusshar Kapoor’s brave and bold decision will open the field of assisted reproduction to many people. Not only the single parents but also the many couples who fervently desire to have a baby may now get the medical assistance to fulfil their nurtured dream.
The IVF /In Vitro fertilization begins with a hormonal treatment for stimulating the woman’s ovulatory process. In this process, the ovum or ova is first are removed from her ovary and then fertilized with the sperm in a liquid in the laboratory. Later the fertilized egg or zygote is cultured for 2-6 days in a growth medium and then the zygote is placed in the mother’s/surrogate mother’s uterus with an intention of having a successful pregnancy.

IVF being the assisted reproductive technique for infertility is also used in the cases of gestational surrogacy. In the cases of gestational surrogacy, the fertilized egg is implanted in the surrogate's uterus, resulting the child being genetically unrelated to the surrogate. Scientists are offering newer ways of reproduction these days, which are proving to be really beneficial for winning the challenges that the people face. Medical science has the answer to infertility to health problems or the age-related issues which become an impediment for becoming parents.

Scientists are offering newer ways of reproduction these days, which are proving to be really beneficial for winning the challenges that the people face. Medical science has the answer to infertility to health problems or the age-related issues which become an impediment for becoming parents.

People are adopting the assisted reproductive technique for fulfilling their dream of becoming parents. The joy of becoming the parent is so overpowering that nowadays people are not showing inhibitions to take up these methods of reproduction, which was a usual problem earlier.
The much loved Bollywood actors and public figures like Aamir Khan and his wife Kiran Rao too took help of surrogacy to have their child Azad Rao Khan. Recently the internet is flooded with the cute photos of Abram, the son of Shah Rukh Khan and Gauri Khan. The couple also took help of surrogacy to welcome Abram in their lives.

We congratulate Tusshar Kapoor on becoming the Papa to his little one Lakshya, May their lives be blessed with joy and happiness.

Source :

Monday, 27 June 2016

Smoking may have negative effects on sperm quality

A recent study found that that sperm of men who smoke has a greater extent of DNA damage than that of non-smokers.

Researchers also assessed 422 proteins in participants' sperm. One protein was absent, 27 proteins were underrepresented, and 6 proteins were over-represented in smokers. Analyses of these proteins suggest that cigarette smoking may promote an inflammatory response in the male reproductive tract.

The BJU International study included 20 nonsmoking men and 20 men who smoked.

"More and more studies are demonstrating a harmful effect of smoking on male fertility. Our results point in the direction of important semen alterations: semen of smokers presents an inflammatory nature, associated with decreased capacity of sperm to achieve fertilization and generate a healthy pregnancy," said Dr. Ricardo Pimenta Bertolla, senior author of the study. "It is especially noteworthy that, in our study, sperm DNA fragmentation was increased. Other studies have proposed this to be a potentially promutagenic effect, which is to say that sperm with altered DNA may lead to health problems in the offspring."


In conclusion, cigarette smoking was associated with an inflammatory state in the accessory glands and in the testis, as shown by enriched proteomic pathways. This state causes an alteration in sperm functional quality, which is characterized by decreased acrosome integrity and mitochondrial activity, as well as by increased nuclear DNA fragmentation.

Reference : M. P. Antoniassi, P. Intasqui Lopes, M. Camargo, D. S. Zylbersztejn, V. M. Carvalho, K. H. M. Cardozo, R. P. Bertolla. Analysis of the sperm functional aspects and seminal plasma proteomic profile from male smokers. BJU International, 2016; DOI: 10.1111/bju.13539

Monday, 20 June 2016

Special Father's Day for dad with cystic fibrosis and his 'miracle' children

Mark Taylor and his family
This Father's Day, Mark Taylor is thanking his lucky stars after finally completing his family.
The 33-year-old, from Bingham, was unlikely to live past 16 due to being born with cystic fibrosis, let alone father two wonderful daughters. Thanks to IVF treatment, Mark and his wife Kate will be enjoying Father's Day with the family they never thought they would have.
The couple recently brought 11-week-old Emily into the world to complete their family with five-year-old Phoebe.

Mark, who works as a sales manager, said: "It's obviously really special for me. I never thought I would have children when I was younger. I was born with cystic fibrosis and there is 99 per cent chance that you will not be able to have children naturally.

"We went through IVF and without that obviously it would have been impossible to have children, so it's a bit of a miracle really. It's amazing that you can do these things nowadays – and being able to spend Father's Day just spending time with my children will be fantastic."

Mr Taylor said he hopes his story will give others with cystic fibrosis belief that they too can have children. "A lot of people with cystic fibrosis don't make it to an age where they can have children, so I'm very lucky to be able to have that and a career as well," he added. "Emily is starting to be a bit more interactive now and she is smiling and playing with her little sister which is fantastic."

Kate, 34, a teaching assistant who is currently on maternity leave, said: "He wasn't expected to live past 16 so he probably never thought about having a family when he was younger. "They're both little miracles and it's going to mean so much to Mark to have them both here on Father's Day. We knew when we started the IVF back in 2007 that there wasn't a definite possibility we would be able to have children, and I just kept expecting something to go wrong. "We have two courses with Phoebe and three with Emily. I think if it wasn't so complicated we would probably have more children, but because of the situation we are in I think that's it for us now – we have our family."

Medical Director, said: "This lovely couple had to go on a very long and difficult journey to have their children. We are delighted to have been able to help them. "They have achieved the impossible, given the challenges of cystic fibrosis, preventing Mark from conceiving naturally. We are extremely happy for them. We would like to send our best wishes for Fathers' Day and for the future."


Friday, 17 June 2016

Cambridge IVF introduces new techology to improve couples’ chances of conceiving

As scientists find new ways to increase success rates the science around IVF is ever-evolving.
And Addenbrooke's fertility clinic Cambridge IVF, based in Trumpington, is introducing new technology in their laboratory that is likely to improve couples' chances of conceiving “Embryoscope timelapse technology”. It has been developed in Sweden and is being introduced in Cambridge following a number of studies assessing its benefits.
Consultant embryologist, said: “This is a really exciting development for people having IVF treatment. The Embryoscope is the market leading-product to allow uninterrupted culture of embryos in an incubator.
"This incubator contains a microscope meaning we can observe the embryos at any point during their development without having to remove them from their controlled environment.
“The Embryoscope records a time-lapse video of the developing embryo. Using this recording we can look for traits similar to those of known good-quality embryos so that we can refine our embryo selection process. This helps to ensure we maximise the chances of a pregnancy."
Use of this technology is beneficial to any patient undergoing IVF treatment but is particularly beneficial to older women and those who have had failed treatments in the past.
“Embryoscope incorporates technology that we believe will be beneficial to all patients but we believe older women and people who have had unsuccessful treatment previously will benefit the most," said Mr Harbottle.
“The technology not only allows us to identify strong embryos but also to select against embryos showing poor potential. At the time of transfer these poor embryos may appear perfectly healthy using standard IVF technology and could be selected for transfer. The enhanced Embryoscope timelapse data can minimise the chances of this happening."
The Embryoscope was created by Swedish company Vitrolife, responsible for a number of innovative solutions for IVF treatment. A number of studies have been conducted to assess the benefits of the scope with several randomised control trials reporting an uplift in clinical outcomes using time-lapse systems.
“The benefit to those having IVF treatment extends further than just the improved success rates. The technology affords us to sit down with patients after treatment and share the time-lapse videos with them at a medical review appointment to show them any patterns in their embryo development, which are of concern. We can also provide patients with a time-lapse video of the embryo or embryos they had transferred as a keepsake, something some people may appreciate."
“We're really excited about this development. We have already had our first couple sign up."


Wednesday, 15 June 2016

Fertility rate in Indian cities lower than those in US, Australia, France

For most people, the general perception about India is of a country sitting on a ticking population bomb. This notion however seems to be somewhat misplaced, at least in the context of the country's urban population, where the fertility rate — the number of children born per woman — has fallen to levels lower even than in countries like the US, France, Australia and New Zealand.

Data from the Sample Registration Survey (SRS) on the total fertility rate (TFR) shows that since 2006 the TFR in urban areas has touched 2 children per woman and from 2010 has fallen below that level. That means there aren't enough children born in Indian cities to replace the existing population of their parents.

For advanced economies, this 'replacement rate' is generally estimated at an average of 2.1. Because of the higher infant mortality rate (IMR) in developing countries, the replacement level fertility rate would be slightly higher and so Indian cities seems to have touched the point where the population would start declining in the absence of migration from rural areas.

Is this an alarming trend?

Experts don't think so: "2.1 is more like a synthetic number. During fertility transition, the total fertility could go below 2.1 and stabilize in a decade or two', says population expert Purushottam M Kulkarni, who recently retired from JNU. Ravinder Kaur, professor of sociology and social anthropology at IIT Delhi, points at a similar pattern of low fertility across Asia and in catholic southern Europe.

"Although the IMR is substantially high as compared to the Western countries but it is not as alarming as it used to be and there is a general confidence among the population that the chances of a child's survival are higher as compared to the past decades and hence the fertility is low", added Kulkarni. Data shows that in 1971, the IMR was 82 (per 1,000 births) and total fertility rate was 4.1 for urban India.

Though the rural fertility rate of 2.5 is higher, it too has witnessed a steep decline. In 1971, the rural fertility rate was 5.4, nearly double its present level. Incidentally in 1952, India became the first country in the world to launch a family planning programme. The sustained government campaign, better access to healthcare facilities, higher female literacy as well as greater participation of women in the workforce have all worked in lowering fertility rates in Indian cities. Many couples prefer one child, although this is not the general norm.

Wednesday, 1 June 2016

By the year 2040, embryo selection will replace sex as the way most of us make babies

Human reproduction is about to undergo a radical shift. Embryo selection, in connection with In-vitro fertilization (IVF), will help our species eliminate many genetic diseases, extend healthy lifespans, and enhance people’s overall well-being. Within 20 years, I predict that it will supplant sex as the way large numbers of us conceive of our children. But while the embryo selection revolution will do a lot of good, it will also raise thorny ethical questions about diversity, equality and what it means to be human–questions we are woefully unprepared to address.

IVF for humans has been around since 1978, the year Louise Brown, the first so-called “test-tube baby,” was born in the UK. Since then, nearly six million infants around the world have been conceived via IVF, with the procedure growing in popularity each year. Starting in the 1990s, doctors began using pre-implantation genetic screening (PGS) to extract cells from early-stage embryos and screen them for simple genetic diseases.

Over time, many genetic diseases will come to be seen as preventable parental lifestyle choices rather than bad luck

At present, over a thousand such diseases, including cystic fibrosis, Huntington’s disease, Tay-Sachs, sickle-cell anemia, and Duchenne muscular dystrophy, can be screened during PGS and the list is growing constantly. With this information, parents using IVF and PGS can select embryos not carrying those diseases if they choose to do so. Some jurisdictions, including the US, Mexico, Italy, and Thailand, also allow parents to select the gender of their future children.

These are still the early days of PGS. The process of linking single gene mutations to specific diseases has been slow and painstaking, but also relatively straightforward. As increasingly more people have their full genomes sequenced, an essential foundation for the future of personalized medicine, scientists will be able to uncover and screen for genetic and epigenetic patterns underpinning far more genetically complex diseases like epilepsy and type 1 diabetes.